EKSTRAK TEH PUTIH SEBAGAI PENGHAMBAT BIOFILM Aggregatibacter actinomycetemcomitans (IN VITRO)

Antibiotic susceptibility of Aggregatibacter actinomycetemcomitans JP2 in a biofilm

BACKGROUND Localized aggressive periodontitis (LAgP) is an inflammatory disease associated with specific bacteria, particularly Aggregatibacter actinomycetemcomitans, which can result in early tooth loss. The bacteria grow as a biofilm known as subgingival plaque. Treatment includes mechanical debridement of the biofilm, often associated with empirical antibiotic treatment. OBJECTIVE The aims...

AI-2 of Aggregatibacter actinomycetemcomitans inhibits Candida albicans biofilm formation

Aggregatibacter actinomycetemcomitans, a Gram-negative bacterium, and Candida albicans, a polymorphic fungus, are both commensals of the oral cavity but both are opportunistic pathogens that can cause oral diseases. A. actinomycetemcomitans produces a quorum-sensing molecule called autoinducer-2 (AI-2), synthesized by LuxS, that plays an important role in expression of virulence factors, in int...

Aggregatibacter actinomycetemcomitans Builds Mutualistic Biofilm Communities in Saliva With Fusobacterium nucleatum and Veillonella sp

Fimbriae-associated genes are biofilm-forming factors in Aggregatibacter actinomycetemcomitans strains.

Aggregatibactor actinomycetemcomitans colonizes human periodontal lesions and is implicated in both aggressive periodontitis and chronic periodontitis. Clinical isolated colonies of A. actinomycetemcomitans were rough type. The rough type has a remarkable ability to adhere tenaciously to solid surfaces and colonize firmly. Rough type colonies change into smooth type colonies during the course o...

Aggregatibacter actinomycetemcomitans builds mutualistic biofilm communities with Fusobacterium nucleatum and Veillonella species in saliva.

Human oral bacterial pathogens grow in attached multispecies biofilm communities. Unattached cells are quickly removed by swallowing. Therefore, surface attachment is essential for growth, and we investigated multispecies community interactions resulting in mutualistic growth on saliva as the sole nutritional source. We used two model systems, saliva-coated transferable solid-phase polystyrene ...